Prior to World War II, Toronto's nascent Greek population of about 3,000 was concentrated in the area bounded by Yonge Street, Carlton Street, Church Street and what is now Dundas Street East. It was this area that was the focus of the 1918 Toronto anti-Greek riot.
In the 1950s, the Danforth saw an influx of Italian immigrants followed by Greek immigrants in the 1960s - many of whom were fleeing political and economic unrest which culminated in the seizure of power by the Greek military junta of 1967–74. In the 1970s and 1980s the Danforth was regarded as the largest Greektown in North America.
Greektown on the Danforth boasts one of the highest concentrations of restaurants per kilometre in the world. The neighbourhood is home to local raconteur Tom Petkos, and is mentioned in the Barenaked Ladies song, "The Old Apartment", and by critically acclaimed author Joseph Assenza in his novel, "The History of John". Several scenes in the movie My Big Fat Greek Wedding were shot here, mentioned on free walking tours of the neighbourhood.